Description

Peanut allergy is one of the most common food allergies. Currently 1-2% of the world population has peanut allergy. Amongst them are many children who suffer from this allergy and the prevalence in children in the US, Europe and Australia has been reported to have doubled over the past 10 years. In the majority of cases peanut allergy is a lifelong disease, making it is also very common amongst  adults. Symptoms are often mild to moderate, but they can unfortunately be life-threatening as well. In highly sensitive patients, even the tiniest amount of peanut protein (sub-milligram) can trigger an allergic reaction. Oral exposure is the most common route for triggering adverse reactions, including the life-threatening ones, but inhalation and skin exposure can also induce symptoms. Central to the adverse reactions to peanut allergens are specific IgE antibodies that are bound to receptors on the surface of mast cells and basophils. Upon exposure to peanut protein, these receptors can be crosslinked, leading to mast cell/basophil degranulation. This can kick-off an individually varying spectrum of allergic symptoms including life-threatening anaphylaxis. This product is a freeze-dried extract of peanut.

Our peanut extract can be used for applications such as:

• • As a diagnostic marker
  • Investigate the development of peanut allergy
  • Develop a therapy against peanut allergy

We have gathered several  mouse models for peanut allergy on this page.
1. CT-Peanut induced Anaphylaxis
2. SEB_Peanut induced Anaphylaxis
3. Adjuvant free Peanut induced sensitisation
4. CT_Peanut induced anaphylaxis in C3H/HeJ
5. Humanized Peanut induced anaphylaxis model

Our main focus is the production of mites, insects and their allergens. Our founders and leading scientists have pharmaceutical, biological and biochemical backgrounds. With over 25 years of experience and an extensive knowledge about mites and insects Citeq is more than just a supplier of allergen source material. We strive for an academic collaboration with our customers in order to achieve the best possible results in research, diagnostics and immunotherapy. We are very pleased to now also contribute to the world of food allergy.