Description

The unique biotinylated Der p 1 extract has been developed especially for research and diagnostic groups. Biotinylated Der p 1 can be used to detect specific antibodies in the serum of animal models and/or patients. For example, in animal models, detecting specific Der p 1 antibodies can demonstrate that the animal has been correctly immunized, or that the animal reacts to treatment (with an increase or decrease in levels of specific antibodies). In patients, the detection of specific Der p 1 antibodies indicates high levels of specific Der p 1 antibodies, which suggests that the patient has a house dust mite allergy.

During biotinylation, biotin is attached to macromolecules or proteins. Biotinylated proteins can be used to detect and/or purify proteins due to the high specificity of biotin-avidin interaction. Citeq has developed house dust mite-related biotinylated proteins, including D. pteronyssinus (HDM) extract and the natural purified Der p 1 and Der p 2 proteins. Biotinylated proteins can be used in many protein assays, such as western blot analysis, fluorescence-activated cell sorting (FACS)/flow cytometry, and enzyme-linked immunosorbent assay (ELISA).

On this page you can read more about biotinylation and the protocol for our biotinylated proteins.