Alternaria alternata mycelium
Extracted mycelium of Alternaria alternata.
Description
Alternaria alternata mold (fungi)
Alternaria alternata belongs to the Pleosporaceae family. Alternaria spores can reach levels of thousands of spores per cubic meter of air in temperate areas from spring to fall. 70% of mold-allergic patients have IgE reactivity to Alternaria. A. alternata spores are especially high in the outdoor air during summertime. Alternaria alternata is an important allergen with mycelial fragments and airborne spores, these characteristics are accountable for the allergic symptoms in human with rhinitis, bronchial asthma or skin diseases.
We have two different forms of A. alternata: medium and mycelium. The word medium might be confusing. Our opinion on this topic is that growing moulds are performed on a medium, above the medium the mycelium is formed. The moulds have grown for 4- 12 weeks. It starts with spores in the medium, these will grow the fungi.
There are 3 separate phases;
• The inoculation phase
• Exponential growing phase
• End phase 9 consolidation phase.
In each growing phase the mould produces different types of sugars and proteins. In the medium soluble parts of the growing mould during the whole period is excreted. Please note that there are different opinions in which part and in which phase allergenic products are produced. Science in mould culture especially moulds which produces allergens is still not finished. So we have made a choice; at harvest we separate the medium and the mycelium. We filtrate the medium so no spores are available, concentrate and dialyse the medium. This product is freeze-dried , we call this the medium part of the mould. We extract the mycelium with a specific buffer, filtrate this , dialyse this and freeze dried, this is the mycelium, part of the moulds.
Read more about dissolving the medium extract on this page. On this page we report on the solubility of lyophilized Alternaria alternata medium extract.
We deliver Alternaria alternata in the following forms:
- Mycellium: We extract the mycelium with a specific buffer, filtrate it, dialyse this and freeze dry it, this is the mycelium; part of the moulds.
- Medium: The medium of the mould extracted, the mould feeds on this medium.
The advantages of our material
- Defined allergen source material, we deliver our material with extensive information about the amount of allergens in our material so you really can tell what you are using for your application.
- Large batches, we produce in large batches so we can deliver from the same batch over a longer period of time. This means you are assured of the same material and consistency. If you are using our material and you are satisfied with it you can even place a reservation of a specific lot so you will receive the same material in the future.
- Freeze-dried, our material will be delivered in freeze-dried form (lyophilization) to assure a long shelf life and can easily be used to reach targeted dilutions.
Additional information
| Size | 10 mg vial, 100 mg vial, 1 gram vial |
|---|
Freeze-dried
Our material will be delivered in freeze-dried (lyophilized) form in different sizes so you always have the right amount available and you are assured of stable material.
Defined
Because of our quality system we produce high quality allergen extracts. Our products will be delivered with a certificate that specifies the amount of allergens, level of endotoxin and much more.
Customization
On request we can customize products for you. Please contact us for any specific requests or collaborations.
Woldwide delivery
Our products are used by researchers and diagnostic companies all over the world. We ship our products with FedEx to your country of choice.
Large batches
We produce large batches so you are assured of material from the same batch over a longer period of time. You can even make a reservation for material from a specific lot.
