Citeq specializes in the production of allergenic extracts. We offer a broad assortment of extracts from house dust and storage mites, insects, molds, food, and plants. In addition to our regular products, we now supply biotinylated extracts for research purposes.

Biotinylated products have a wide range of applications in the field of respiratory allergy, as many techniques are compatible with them. Due to the high specificity and strength of the biotin-avidin interaction, biotinylation can be used to detect and/or purify proteins. Biotinylated products could be included in various settings of experiments with animal models as the analysis tool to confirm the proper immunization of the subjects or to verify their response to treatment. Additionally, they could help quantify the complex responses from the immune system to make research and diagnosis as precise as possible.

During biotinylation, biotin is attached to macromolecules or proteins. The choice of the functional group to add to biotin is quite large, as a variety of molecules could be attached to it. Besides, it could be used in a different experimental setting with various mediums as the biotin-avidin interaction is not affected by the changes in pH, temperature and other factors. The biotinylated products could also be utilized with standard methods, such as western blot analysis, fluorescence-activated cell sorting (FACS)/ flow cytometry and enzyme-linked immunosorbent assay (ELISA). When a 96 Microwell plate is used, one vial of biotinylated allergens is sufficient to coat two plates.

Our biotinylated assortment

• Dermatophagoides pteronyssinus extract
• Dermatophagoides farinae extract
• der p 1
• der f 1
• Acarus siro extract
• Blomia tropicalis extract
• Glycyphagus domesticus extract
• Lepidoglyphus destructor extract
• Tyrophagus putrescentiae extract
• Cat dander extract (coming soon)
• Dog dander extract (coming soon
• Pollen extracts (coming soon)
• Venom extracts (coming soon)
• Mould extracts (coming soon)

Citeq has been contributing to the field of allergy research, both therapeutics and diagnostics, for over 25 years. We specialize in house dust mites, insects and moulds and have mainly been delivering well-defined allergen source material for research and development. We are happy to announce that our R&D team successfully manufactured biotinylated  allergens. If you need more information, please contact us. Citeq always aims to optimally serve the research community, as we have always done in the field of respiratory allergy.